The Northwestern Wildcats will look to extend one winning streak and end another when they host the Duke Blue Devils on Friday at Northwestern Medicine Field at Martin Stadium in Evanston, Ill. Northwestern (1-0) started its 2024 season with its fifth straight win since last season, a 13-6 home victory over Miami (OH). However, the Wildcats have lost their last five meetings with Duke and trail 13-10 in the standings. The Blue Devils (1-0) are seeking their third consecutive 2-0 start to the season after defeating Elon 26-3 in their opener.

Kickoff is scheduled for 9 p.m. ET. The Wildcats are a 1.5-point favorite in the latest Northwestern vs. Duke odds from SportsLine Consensus, while the over/under for total points is set at 37. Before making any Duke vs. Northwestern picks or CFB predictions, you need to see what the SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated over $2,000 in profit for $100 players on its top-rated college football picks against the spread. It also has a profitable 13-9 season with the top rated spread picks. Everyone who has followed it has seen STRONG returns!

The model knows that Northwestern has won three consecutive non-conference games for the first time since 2016-17 and is looking for its first six-game winning streak since 2019-20. Quarterback Mike Wright led the Wildcats offensively in their season-opening victory, completing 18 of 30 pass attempts for 178 yards and scoring his team’s best 65-yard run and their only touchdown. The defense played a major role in the win, limiting Miami (OH) to 40 yards on the ground and recording four sacks and two interceptions, leaving Northwestern without allowing a TD for the first time since its 2020 season opener against Maryland.

The model also factored in that Duke also had a strong defensive performance in its first game of the year. The Blue Devils allowed just 140 yards, including 30 rushing yards, and recorded eight sacks and 16 tackles for loss against Elon. Quarterback Maalik Murphy threw for 291 yards and two touchdowns in his debut at Duke after transferring from Texas, while wideout Jordan Moore caught seven passes for 112 yards.

The model has simulated Northwestern vs. Duke 10,000 times and the results are in. We can tell you that the model is overall biased too far, and it also says that one side of the range is correct well over 60% of the time!

Who wins Duke vs. Northwestern, and which side of the range applies in well over 60% of cases? … Join SportsLine now and find out which side of the spread you should be on, based on the 13-9 odds model on the highest-rated CFB picks!